His 1929 film with Louis Buñuel, Un Chien Andalou, contains a character described as a 'hermaphrodite'.
He offered to do a painting of April Ashley as Hermaphroditos but she did not want to immortalized in her half-way status.
From the 1960s he was and remained a friend and mentor of Amanda Lear, and rumours say that he paid for her operation with Dr Burou in Casablanca in 1963. She lived with him and his wife for many years. Some say that her name = ‘a man’ + ‘dali’ or "L’amant Dali”.
In 1965 Mario Montez the New York underground film female impersonator made his iconic Andy Warhol film, Screen test Number 2. the one where he confronted about his gender and admits that he is a man, but he does so, he says, only because he is a woman. Savador Dalí was present and is in the film.
Also in the 1970s he was a friend of International Chrysis, the New York drag celebrity, most famous for her role in Sidney Lumet's 1990 film Q & A. He appears in the 1992 documentary film about her life, Split: William to Chrysis: Portrait of a Drag Queen.
In the late 1970s, Dalí was close to the Brazilian 'trans diva', Yeda Brown. He introduced her to musicians and the press called her ‘the muse of Dalí’.