He initially thought of himself as homosexual, but in exploring homosexuality found out that he was not. He was introduced to the Harry Benjamin practice, possibly by Wardell Pomeroy of the Kinsey Institute.
Hoff was a guest on the the NBC television program Not for Women Only where he explained transsexualism from a medical viewpoint referring to trans women as 'men' as was the then practice.
"You can say that you know that you are a woman, therefore you want to be one. But no woman I have ever asked has been able to tell me what that means, and I doubt that transsexuals will be the first to define it."He took over the Harry Benjamin practice in New York in 1976, after Benjamin's successor Charles Ihlenfeld resigned to begin a psychiatric residency in the Bronx. This was his first clinic practice other than the residency in St Louis. The practice was being managed under the aegis of the Orentreich Medical Group, a dermatology and hair restoration practice, and was located at 1 East 72nd St. It was then still administered by Benjamin's office manager and assistant Virginia Allen.
Hoff fired Virginia, the nurse, Mary Ryan, and the physician, Agnes Nagy. He pleased Dr Orentreich by moving the practice downtown to a townhouse he had bought behind the Chelsea Hotel. In this period Dr Hoff confronted Charles Socarides and his reactionary views that homosexuality can be cured by psychoanalysis, and had punk musician Jayne County as a patient.
Hoff transitioned to Jeanne and had surgery with Dr Granato in 1977. She was interviewed at home by Lynn Redgrave and Frank Fields immediately before surgery and two months afterwards. The resulting television program "Becoming Jeanne" won the prestigious Ohio State Broadcasting award in 1979.
By 1980 there were few patients left in the practice, and Hoff had already taken a job in a psych ward in Brooklyn. The next year she sold the building and moved away, first to Massachusetts and then California.
She became a psychiatrist at San Quentin prison. She was in the news in April-May 1998 when she was the only one of three psychiatrists to testify that murderer Horace Kelly might be competent to be executed, and the defense attorney attempted to impeach Hoff.
She is now retired and in 2013 donated her archives to the Kinsey Institute.
- "Masculine, Feminine or Androgynous?" Not for Women Only. WNBC 1976 hosted by Polly Bergen and Frank Fields, produced by Madeline Amgott. Online at: www.kinseyinstitute.org/library/jeannehoff.html.
- Becoming Jeanne…A Search for Sexual Identity. NBC 30 June 1978. Online here. Jeanne Hoff interviewed by Lynn Redgrave and Frank Fields. Online at: www.kinseyinstitute.org/library/jeannehoff.html.
- Jeanne Hoff. "Multiple personality disorder?" The Journal of clinical psychiatry, 48(4), Apr 1987.
- Jayne County with Rupert Smith. Man Enough to be a Woman. London: Serpent's Tail, 1995: 99-100.
- Michael Dougan. "Killer's mental records turn up". SFGate, April 17, 1998. http://www.sfgate.com/news/article/Killer-s-mental-records-turn-up-3094483.php,
- Maria L LaGanga. "Killer Understands He Faces Execution, Prosecutor Says". Los Angeles Times, May 01, 1998. http://articles.latimes.com/1998/may/01/news/mn-45268.
- Michael Dougan. "Sanity trial outcome rests with minutiae". SFGate, May 5, 1998. http://www.sfgate.com/default/article/Sanity-trial-outcome-rests-with-minutiae-3092031.php.
- Sara Catania. "The Alienists: Where experts divide, jury must decide". LAWeekly, May 13 1998. http://www.laweekly.com/1998-05-21/news/the-alienists.
- Andy Humm. "Socarides, Leading Anti-Gay Shrink, Dies". Gay City, 4,52 Dec 29-Jan 4, 2005. http://gaycitynews.com/gcn_452/newsbriefs.html.
- "Jeanne Hoff Archive". The Kinsey Institute. www.kinseyinstitute.org/library/jeannehoff.html.
- SJ Parker. Emails to Zagria, 15,17 September 2013.
Although Horace Kelly's lawyer subpoenaed Hoff's prison personnel file in an attemp to impeach her, he presumably hadn't heard rumours that she was transsexual, didn't find it in the file and didn't read her. Otherwise he probably would have used it to defame her. She had been in the 1978 televison special under the same name, but that was 20 years earlier. Before the internet it was much more difficult to make connections.
++Jeanne was also, in effect, outed in Jayne County's 1995 autobiography, but presumably the lawyer didn't read punk biographies.